| Date | Location | Result | |
| 04/02/22 | New Orleans, LA | #3 Kansas 81, #6 Villanova 65 | Box score |
| 03/31/22 | New York, NY | Xavier 73, Texas A&M 72 | Box score |
| 03/29/22 | New York, NY | Xavier 84, St. Bonaventure 77 | Box score |
| 03/26/22 | San Antonio, TX | #6 Villanova 50, #15 Houston 44 | Box score |
| 03/25/22 | Chicago, IL | #3 Kansas 66, #13 Providence 61 | Box score |
| 03/24/22 | San Antonio, TX | #6 Villanova 63, Michigan 55 | Box score |
| 03/22/22 | Cincinnati, OH | Xavier 75, Vanderbilt 73 | Box score |
| 03/20/22 | Cincinnati, OH | Xavier 72, Florida 56 | Box score |
| 03/20/22 | Pittsburgh, PA | #6 Villanova 71, Ohio State 61 | Box score |
| 03/19/22 | Buffalo, NY | #13 Providence 79, Richmond 51 | Box score |
| 03/19/22 | Fort Worth, TX | #3 Kansas 79, Creighton 72 | Box score |
| 03/18/22 | Pittsburgh, PA | #6 Villanova 80, Delaware 60 | Box score |
| 03/18/22 | San Diego, CA | TCU 69, Seton Hall 42 | Box score |
| 03/17/22 | Buffalo, NY | New Mexico St. 70, #21 Connecticut 63 | Box score |
| 03/17/22 | Buffalo, NY | #13 Providence 66, South Dakota St. 57 | Box score |
| 03/17/22 | Fort Worth, TX | North Carolina 95, Marquette 63 | Box score |
| 03/17/22 | Fort Worth, Texas | Creighton 72, San Diego State 69 | Box score |
| 03/15/22 | Cincinnati, OH | Xavier 72, Cleveland St. 68 | Box score |
| 03/12/22 | New York, NY | #8 Villanova 54, Creighton 48 | Box score |
| 03/11/22 | New York, NY | #8 Villanova 63, #20 Connecticut 60 | Box score |
| 03/11/22 | New York, NY | Creighton 85, #11 Providence 58 | Box score |
| 03/10/22 | New York, NY | #20 Connecticut 62, Seton Hall 52 | Box score |
| 03/10/22 | New York, NY | #8 Villanova 66, St. John's 65 | Box score |
| 03/10/22 | New York, NY | Creighton 74, Marquette 63 | Box score |
| 03/10/22 | New York, NY | #11 Providence 65, Butler 61 | Box score |
| 03/09/22 | New York, NY | Seton Hall 57, Georgetown 53 | Box score |
| 03/09/22 | New York, NY | St. John's 92, DePaul 73 | Box score |
| 03/09/22 | New York, NY | Butler 89, Xavier 82 | Box score |
| 03/05/22 | Cincinnati, OH | Xavier 97, Georgetown 75 | Box score |
| 03/05/22 | Indianapolis, IN | #11 Villanova 78, Butler 59 | Box score |
| 03/05/22 | Omaha, Neb. (CHI | Seton Hall 65, Creighton 60 | Box score |
| 03/05/22 | Milwaukee, WI | Marquette 85, St. John's 77 | Box score |
| 03/05/22 | Mansfield, CT | #18 Connecticut 75, DePaul 68 | Box score |
| 03/02/22 | Queens, NY | St. John's 81, Xavier 66 | Box score |
| 03/02/22 | Newark, NJ | Seton Hall 73, Georgetown 68 | Box score |
| 03/02/22 | Chicago, IL | DePaul 91, Marquette 80 | Box score |
| 03/02/22 | Omaha, Neb. (CHI | Creighton 64, #18 Connecticut 62 | Box score |
| 03/01/22 | Villanova, Pa. | #11 Villanovay 76, #9 Providence 74 | Box score |
| 02/27/22 | Washington, DC | #21 Connecticut 86, Georgetown 77 | Box score |
| 02/27/22 | Chicago, IL | DePaul 99, St. John's 94 | Box score |
| 02/26/22 | Cincinnati, OH | Seton Hall 82, Xavier 66 | Box score |
| 02/26/22 | Providence, RI | #11 Providence 72, Creighton 51 | Box score |
| 02/26/22 | Milwaukee, WI | Marquette 64, Butler 56 | Box score |
| 02/24/22 | Washington, DC | DePaul 68, Georgetown 65 | Box score |
| 02/23/22 | Queens, NY | Creighton 81, St. John's 78 | Box score |
| 02/23/22 | Newark, NJ | Seton Hall 66, Butler 60 | Box score |
| 02/23/22 | Providence, RI | #11 Providence 99, Xavier 92 | Box score |
| 02/22/22 | Hartford, Conn. | #21 Connecticut 71, #8 Villanova 69 | Box score |
| 02/20/22 | Indianapolis, IN | #8 Providence 71, Butler 70 | Box score |
| 02/20/22 | Omaha, Neb. (CHI | Creighton 83, Marquette 82 | Box score |
| 02/19/22 | Bryn Mawr, PA | #10 Villanova 74, Georgetown 66 | Box score |
| 02/19/22 | Mansfield, CT | #24 Connecticut 72, Xavier 61 | Box score |
| 02/19/22 | Newark, NJ | Seton Hall 66, DePaul 64 | Box score |
| 02/18/22 | Queens, NY | St. John's 91, Butler 57 | Box score |
| 02/17/22 | Chicago, IL | Creighton 71, DePaul 59 | Box score |
| 02/16/22 | Cincinnati, OH | St. John's 86, Xavier 73 | Box score |
| 02/16/22 | Mansfield, CT | #24 Connecticut 70, Seton Hall 65 | Box score |
| 02/16/22 | Milwaukee, WI | Marquette 77, Georgetown 66 | Box score |
| 02/15/22 | Providence, RI | #10 Villanova 89, #8 Providence 84 | Box score |
| 02/15/22 | Chicago, IL | Butler 73, DePaul 71 | Box score |
| 02/14/22 | Omaha, Neb. (CHI | Creighton 88, Georgetown 77 | Box score |
| 02/13/22 | New York, NY | #24 Connecticut 63, St. John's 60 | Box score |
| 02/12/22 | Philadelphia, PA | #15 Villanova 73, Seton Hall 67 | Box score |
| 02/12/22 | Providence, RI | #11 Providence 76, DePaul 73 | Box score |
| 02/12/22 | Washington, DC | Creighton 80, Georgetown 66 | Box score |
| 02/12/22 | Indianapolis, IN | Butler 85, #18 Marquette 79 | Box score |
| 02/11/22 | Cincinnati, OH | #25 Xavier 74, #24 Connecticut 68 | Box score |
| 02/09/22 | Newark, NJ | Seton Hall 73, #25 Xavier 71 | Box score |
| 02/09/22 | Chicago, IL | DePaul 82, Georgetown 74 | Box score |
| 02/08/22 | New York, NY | #15 Villanova 75, St. John's 69 | Box score |
| 02/08/22 | Mansfield, CT | #24 Connecticut 80, #18 Marquette 72 | Box score |
| 02/08/22 | Omaha, Neb. (CHI | Creighton 54, Butler 52 | Box score |
| 02/06/22 | Washington, DC | #15 Providence 71, Georgetown 52 | Box score |
| 02/05/22 | Cincinnati, OH | DePaul 69, #21 Xavier 65 | Box score |
| 02/05/22 | Philadelphia, PA | #12 Villanova 85, #17 Connecticut 74 | Box score |
| 02/05/22 | Indianapolis, IN | St. John's 75, Butler 72 | Box score |
| 02/04/22 | Newark, NJ | Seton Hall 74, Creighton 55 | Box score |
| 02/03/22 | Washington, DC | St. John's 90, Georgetown 77 | Box score |
| 02/02/22 | Cincinnati, OH | #21 Xavier 68, Butler 66 | Box score |
| 02/02/22 | Milwaukee, WI | #24 Marquette 83, #12 Villanova 73 | Box score |
| 02/01/22 | Mansfield, CT | Creighton 59, #17 Connecticut 55 | Box score |
| 02/01/22 | Queens, NY | #15 Providence 86, St. John's 82 | Box score |
| 02/01/22 | Washington, DC | Seton Hall 70, Georgetown 63 | Box score |
| 01/30/22 | Providence, RI | #17 Providence 65, #22 Marquette 63 | Box score |
| 01/29/22 | Bryn Mawr, PA | #14 Villanova 73, St. John's 62 | Box score |
| 01/29/22 | Chicago, IL | #20 Connecticut 57, DePaul 50 | Box score |
| 01/29/22 | Omaha, Neb. (CHI | #21 Xavier 74, Creighton 64 | Box score |
| 01/29/22 | Indianapolis, IN | Butler 56, Georgetown 53 | Box score |
| 01/26/22 | Cincinnati, OH | #17 Providence 65, #21 Xavier 62 | Box score |
| 01/26/22 | Newark, NJ | #22 Marquette 73, Seton Hall 63 | Box score |
| 01/26/22 | Indianapolis, IN | Butler 72, Creighton 55 | Box score |
| 01/25/22 | Bryn Mawr, PA | #14 Villanova 67, DePaul 43 | Box score |
| 01/25/22 | Mansfield, CT | #20 Connecticut 96, Georgetown 73 | Box score |
| 01/24/22 | South Orange, NJ | St. John's 84, Seton Hall 63 | Box score |
| 01/23/22 | Milwaukee, WI | Marquette 75, #20 Xavier 64 | Box score |
| 01/23/22 | Providence, RI | #21 Providence 69, Butler 62 | Box score |
| 01/22/22 | Washington, DC | #11 Villanova 85, Georgetown 74 | Box score |
| 01/22/22 | New York, NY | Seton Hall 66, St. John's 60 | Box score |
| 01/22/22 | Omaha, Neb. (CHI | Creighton 60, DePaul 47 | Box score |
| 01/20/22 | Providence, RI | #21 Providence 83, Georgetown 75 | Box score |
| 01/20/22 | Indianapolis, IN | #25 Connecticut 75, Butler 56 | Box score |
| 01/19/22 | Chicago, IL | #20 Xavier 68, DePaul 67 | Box score |
| 01/19/22 | Bryn Mawr, PA | Marquette 57, #11 Villanova 54 | Box score |
| 01/19/22 | Omaha, Neb. (CHI | Creighton 87, St. John's 64 | Box score |
| 01/18/22 | Hartford, CT | No. 25 Connecticut 76, Butler 59 | Box score |
| 1/16/22 | New York, N.Y. | St. John's 88, Georgetown 69 | Box score |
| 01/16/22 | Philadelphia, PA | #14 Villanova 82, Butler 42 | Box score |
| 01/15/22 | Cincinnati, OH | #17 Xavier 80, Creighton 73 | Box score |
| 01/15/22 | Milwaukee, WI | Marquette 73, #20 Seton Hall 72 | Box score |
| 01/13/22 | Chicago, IL | DePaul 96, #20 Seton Hall 92 | Box score |
| 01/13/22 | Washington, DC | Butler 72, Georgetown 58 | Box score |
| 01/12/22 | Cincinnati, OH | #14 Villanova 64, #17 Xavier 60 | Box score |
| 1/12/22 | Storrs, Conn. | Connecticut 86, St. John's 78 | Box score |
| 01/11/22 | Milwaukee, WI | Marquette 87, DePaul 76 | Box score |
| 01/08/22 | Chicago, IL | #19 Villanova 79, DePaul 64 | Box score |
| 01/08/22 | Newark, NJ | #24 Seton Hall 90, Connecticut 87 | Box score |
| 1/8/22 | Providence, R.I. | #16 Providence 83, St. John's 73 | Box score |
| 01/07/22 | Indianapolis, IN | #22 Xavier 87, Butler 72 | Box score |
| 01/07/22 | Washington, DC | Marquette 92, Georgetown 64 | Box score |
| 01/05/22 | Bryn Mawr, PA | #19 Villanova 75, Creighton 41 | Box score |
| 1/5/22 | Queens, N.Y. | St. John's 89, DePaul 84 | Box score |
| 01/04/22 | Indianapolis, IN | #24 Seton Hall 71, Butler 56 | Box score |
| 01/04/22 | Milwaukee, WI | Marquette 88, #16 Providence 56 | Box score |
| 01/01/22 | Newark, NJ | #22 Villanova 73, #15 Seton Hall 67 | Box score |
| 01/01/22 | Chicago, IL | #21 Providence 70, DePaul 53 | Box score |
| 01/01/22 | Milwaukee, WI | Creighton 75, Marquette 69 | Box score |
| 12/29/21 | Providence, RI | #21 Providence 70, #15 Seton Hall 65 | Box score |
| 12/29/21 | Indianapolis, IN | Butler 63, DePaul 59 | Box score |
| 12/21/21 | Milwaukee, WI | Connecticut 78, Marquette 70 | Box score |
| 12/21/21 | Bryn Mawr, PA | #23 Villanova 71, #18 Xaxier 58 | Box score |
| 12/18/21 | Cincinnati, OH | #22 Xaxier 80, Marquette 71 | Box score |
| 12/18/21 | New York, N.Y. | Pittsburgh 59, St. John's 57 | Box score |
| 12/18/21 | Mansfield, CT | Providence 57, #20 Connecticut 53 | Box score |
| 12/18/21 | Washington, DC | TCU 80, Georgetown 73 | Box score |
| 12/18/21 | Indianapolis, IN | #3 Purdue 77, Butler 48 | Box score |
| 12/17/21 | Omaha, Neb. (CHI | Creighton 79, #9 Villanova 59 | Box score |
| 12/15/21 | Cincinnati, OH | #22 Xavier 86, Morehead St. 63 | Box score |
| 12/15/21 | Washington, DC | Georgetown 85, Howard 73 | Box score |
| 12/14/21 | Chicago, IL | DePaul 72, UIC 66 | Box score |
| 12/14/21 | Omaha, Neb. (CHI | Arizona State 58, Creighton 57 | Box score |
| 12/12/21 | Waco, TX | #2 Baylor 57, #6 Villanova 36 | Box score |
| 12/12/21 | Newark, NJ | #23 Seton Hall 77, Rutgers 63 | Box score |
| 12/12/21 | Queens, N.Y. | St. John's 82, Colgate 64 | Box score |
| 12/11/21 | Cincinnati, OH | Xavier 83, Cincinnati 63 | Box score |
| 12/11/21 | Newark, NJ | #15 Connecticut 74, St. Bonaventure 64 | Box score |
| 12/11/21 | Providence, RI | Providence 68, Central Connecticut 53 | Box score |
| 12/11/21 | Milwaukee, WI | #4 UCLA 67, Marquette 56 | Box score |
| 12/11/21 | Washington, DC | Georgetown 79, Syracuse 75 | Box score |
| 12/11/21 | Sioux Falls, SD | Creighton 83, #24 BYU 71 | Box score |
| 12/11/21 | Indianapolis, IN | Butler 66, Eastern Illinois 54 | Box score |
| 12/10/21 | Louisville, KY | DePaul 62, Louisville 55 | Box score |
| 12/08/21 | Manhattan, KS | Marquette 64, Kansas State 63 | Box score |
| 12/9/21 | Queens, NY | St. John's 88, Monmouth 83 | Box score |
| 12/09/21 | Newark, NJ | #23 Seton Hall 64, #7 Texas 60 | Box score |
| 12/08/21 | Cincinnati, OH | Xavier 96, Ball State 50 | Box score |
| 12/08/21 | Morgantown, WV | West Virginia 56, #15 Connecticut 53 | Box score |
| 12/08/21 | Washington, DC | Georgetown 100, UMBC 71 | Box score |
| 12/07/21 | New York, NY | #6 Villanova 67, Syracuse 53 | Box score |
| 12/07/21 | Providence, RI | Providence 68, Vermont 58 | Box score |
| 12/07/21 | Chicago, IL | DePaul 87, Duquesne 67 | Box score |
| 12/07/21 | Norman, OK | Butler 66, Oklahoma 62 | Box score |
| 12/05/21 | Stillwater, OK | Xavier 77, Oklahoma State 71 | Box score |
| 12/5/21 | Queens, N.Y. | St. John's 83, Fordham 69 | Box score |
| 12/05/21 | Columbia, SC | South Carolina 80, Georgetown 67 | Box score |
| 12/04/21 | Bryn Mawr, PA | #6 Villanova 81, Saint Joseph's 52 | Box score |
| 12/04/21 | Mansfield, CT | #17 Connecticut 88, Grambling 59 | Box score |
| 12/04/21 | South Orange, NJ | #25 Seton Hall 113, Nyack 67 | Box score |
| 12/04/21 | Providence, RI | Providence 66, Rhode Island 52 | Box score |
| 12/04/21 | Madison, WI | #23 Wisconsin 89, Marquette 76 | Box score |
| 12/04/21 | Chicago, IL | Loyola Chicago 68, DePaul 64 | Box score |
| 12/04/21 | Omaha, Neb. (CHI | #19 Iowa State 64, Creighton 58 | Box score |
| 12/3/21 | Elmont, N.Y. (UBS | #8 Kansas 95, St. John's 75 | Box score |
| 12/01/21 | Cincinnati, OH | Xavier 78, Central Michigan 45 | Box score |
| 12/01/21 | Philadelphia, PA | #6 Villanova 71, Penn 56 | Box score |
| 12/01/21 | Newark, NJ | #25 Seton Hall 85, Wagner 63 | Box score |
| 12/01/21 | Providence, RI | Providence 72, Texas Tech 68 | Box score |
| 11/30/21 | Mansfield, CT | #17 Connecticut 72, UMES 63 | Box score |
| 11/30/21 | Milwaukee, WI | Marquette 83, Jackson State 54 | Box score |
| 11/30/21 | Washington, DC | Georgetown 91, Longwood 83 | Box score |
| 11/30/21 | Omaha, Neb. (CHI | Creighton 80, North Dakota State 55 | Box score |
| 11/30/21 | Indianapolis, IN | Butler 68, Saginaw Valley 57 | Box score |
| 11/28/21 | Philadelphia, PA | #7 Villanova 72, La Salle 46 | Box score |
| 11/28/21 | Newark, NJ | #21 Seton Hall 84, Bethune-Cookman 70 | Box score |
| 11/28/21 | Chicago, IL | DePaul 101, Eastern Michigan 63 | Box score |
| 11/27/21 | Queens, N.Y. | St. John's 77, NJIT 68 | Box score |
| 11/27/21 | Providence, RI | Providence 85, Saint Peter's 71 | Box score |
| 11/27/21 | Milwaukee, WI | Marquette 80, Northern Illinois 66 | Box score |
| 11/27/21 | Omaha, Neb. (CHI | Creighton 70, SIUE 65 | Box score |
| 11/26/21 | Brooklyn, NY | #25 Xavier 59, Virginia Tech 58 | Box score |
| 11/26/21 | Paradise Island | #22 Connecticut 70, VCU 63 | Box score |
| 11/26/21 | Anaheim, CA | Saint Joseph's 77, Georgetown 74 | Box score |
| 11/26/21 | Chicago, IL | DePaul 77, Northern Kentucky 68 | Box score |
| 11/25/21 | Anaheim, CA | San Diego State 73, Georgetown 56 | Box score |
| 11/25/21 | Paradise Island | Michigan State 64, #22 Connecticut 60 | Box score |
| 11/24/21 | Las Vegas, NV | Butler 84, Charminade 51 | Box score |
| 11/24/21 | Fort Myers, FL | #21 Seton Hall 62, California 59 | Box score |
| 11/24/21 | Paradise Island | #22 Connecticut 115, #19 Auburn 109 | Box score |
| 11/24/21 | Brooklyn, NY | Iowa State 82, #25 Xavier 70 | Box score |
| 11/23/21 | Queens, N.Y. | St. John's 76, St. Francis Brooklyn 70 | Box score |
| 11/23/21 | Newark, NJ | Virginia 58, Providence 40 | Box score |
| 11/23/21 | Las Vegas, NV | Texas A&M 57, Butler 50 | Box score |
| 11/22/21 | Fort Myers, FL | Ohio State 79, #21 Seton Hall 76 | Box score |
| 11/22/21 | Newark, NJ | Providence 77, Northwestern 72 | Box score |
| 11/22/21 | Charlotte Amalie | Creighton 66, Southern Illinois 64 | Box score |
| 11/22/21 | Las Vegas, NV | #12 Houston 70, Butler 52 | Box score |
| 11/21/21 | Cincinnati, OH | Xavier 88, Norfolk State 48 | Box score |
| 11/21/21 | Uncasville, CT | #6 Purdue 80, #5 Villanova 74 | Box score |
| 11/21/21 | Charleston, SC | #22 St. Bonaventure 70, Marquette 54 | Box score |
| 11/21/21 | Charlotte Amalie | Colorado St. 95, Creighton 81 | Box score |
| 11/20/21 | Uncasville, CT | #5 Villanova 71, #17 Tennessee 53 | Box score |
| 11/20/21 | Mansfield, CT | Connecticut 87, Binghamton 63 | Box score |
| 11/20/21 | Queens, N.Y. | St. John's 87, Fairleigh Dickinson 74 | Box score |
| 11/20/21 | Chicago, IL | DePaul 84, Western Illinois 80 | Box score |
| 11/19/21 | Charleston, SC | Marquette 82, West Virginia 71 | Box score |
| 11/19/21 | Washington, DC | Georgetown 83, Siena 65 | Box score |
| 11/19/21 | Charlotte Amalie | Creighton 78, Brown 57 | Box score |
| 11/18/21 | Chicago, IL | DePaul 73, Rutgers 70 | Box score |
| 11/18/21 | Cincinnati, OH | Xavier 71, #19 Ohio State 65 | Box score |
| 11/18/21 | Providence, RI | Providence 69, New Hampshire 58 | Box score |
| 11/18/21 | Charleston, SC | Marquette 78, Ole Miss 72 | Box score |
| 11/17/21 | Mansfield, CT | Connecticut 93, LIU 40 | Box score |
| 11/17/21 | Bloomington, Ind. | Indiana 76, St. John's 74 | Box score |
| 11/17/21 | Indianapolis, IN | Michigan State 73, Butler 52 | Box score |
| 11/16/21 | Ann Arbor, MI | Seton Hall 67, #4 Michigan 65 | Box score |
| 11/16/21 | Washington, DC | Georgetown 79, American 57 | Box score |
| 11/16/21 | Bryn Mawr, PA | #5 Villanova 100, Howard 81 | Box score |
| 11/16/21 | Lincoln, NE | Creighton 77, Nebraska 69 | Box score |
| 11/15/21 | Madison, WI | Providence 63, Wisconsin 58 | Box score |
| 11/15/21 | Milwaukee, WI | Marquette 67, #10 Illinois 66 | Box score |
| 11/14/21 | Newark, NJ | Seton Hall 80, Yale 44 | Box score |
| 11/13/21 | Indianapolis, IN | Butler 70, Troy 59 | Box score |
| 11/13/21 | Chicago, IL | DePaul 99, Central Michigan 66 | Box score |
| 11/13/21 | Queens, NY | St. John's 91, Saint Peter's 70 | Box score |
| 11/13/21 | Washington, DC | Dartmouth 69, Georgetown 60 | Box score |
| 11/13/21 | Mansfield, CT | Connecticut 89, Coppin State 54 | Box score |
| 11/12/21 | Los Angeles, CA | #2 UCLA 86, #4 Villanova 77 | Box score |
| 11/12/21 | Milwaukee, WI | Marquette 75, New Hampshire 70 | Box score |
| 11/12/21 | Indianapolis, IN | Butler 85, Central Arkansas 53 | Box score |
| 11/12/21 | Cincinnati, OH | Xavier 73, Kent St. 59 | Box score |
| 11/11/21 | Providence, RI | Providence 92, Sacred Heart 64 | Box score |
| 11/11/21 | Omaha, NE | Creighton 51, Kennesaw St. 44 | Box score |
| 11/10/21 | Chicago, IL | DePaul 97, Coppin State 72 | Box score |
| 11/10/21 | Newark, NJ | Seton Hall 93, Fairleigh Dickinson 49 | Box score |
| 11/09/21 | Milwaukee, WI | Marquette 88, SIUE 77 | Box score |
| 11/09/21 | Omaha, NE | Creighton 90, Ark.-Pine Bluff 77 | Box score |
| 11/09/21 | Queens, NY | St. John's 119, Mississippi Valley 61 | Box score |
| 11/09/21 | Cincinnati, OH | Xavier 63, Niagara 60 | Box score |
| 11/09/21 | Providence, RI | Providence 80, Fairfield 73 | Box score |
| 11/09/21 | Indianapolis, IN | Butler 56, IUPUI 47 | Box score |
| 11/09/21 | Mansfield, CT | Connecticut 99, Central Connecticut 48 | Box score |
| 11/09/21 | Bryn Mawr, PA | Villanova 91, Mount St. Mary's 51 | Box score |